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Cialis (tadalafil) is a prescription PDE5 inhibitor used to treat male impotence. This drug is intended for men only and is not supposed to be taken by females. Before taking this medicine make sure you tell your health care provider about any health conditions or illnesses you have or used to have as these may interfere with your treatment. You must not start taking Cialis if you are currently using nitrates (isosorbide dinitrate, isosorbide mononitrate, or nitroglycerin). If you are not sure whether the meds you are using are nitrates it’s best to consult your health care provider first and only then ask for the prescription or buy Cialis online on your own. If you are taking any drugs at the moment, it’s a good idea to make a list of them for your health care provider to see. Some medicines have been reported to increase the effects of Cialis, while others decrease these effects o alter them, which means you may not get the results you are expecting. If you are using any of the following medications make sure your health care provider is aware of each and every one of them: troleandomycin, phenobarbital, clarithromycin, amiodarone, fluvoxamine, aprepitant, dexamethasone, saquinavir, carbamazepine, cimetidine, certain erectile dysfunction drugs, metronidazole, rifampin, ritonavir, fluoxetine, isoniazid, erythromycin, HIV protease inhibitors, danazol, alpha blockers, high blood pressure, efavirenz, sertraline, rifabutin, as well as certain antifungals, such as ketoconazole. Tadalafil offers the longest period of efficiency – up to 36 hours, which means there is no more need to plan your sex life by minutes.